BDBM287960 (5-(2-((2-(4-(dimethylamino)-2- methylphenyl)quinazolin-4-yl)amino)- 1-phenylethyl)-1H-pyrrol-2- yl)methanol::US10087148, Example 28

SMILES CN(C)c1ccc(c(C)c1)-c1nc(NCC(c2ccc(CO)[nH]2)c2ccccc2)c2ccccc2n1

InChI Key InChIKey=YTSCUSRFYSZBCC-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 287960   

TargetSodium-dependent dopamine transporter(Human)
The United States of America As Represented By The Secretary, Department of Health and Human Services Office of Technology Transfer, National Institute of Health

US Patent
LigandPNGBDBM287960((5-(2-((2-(4-(dimethylamino)-2- methylphenyl)quina...)
Affinity DataEC50:  18nMpH: 7.4Assay Description:Uptake inhibition assay for the dopamine transporter was conducted in rat brain synaptosomes as described elsewhere with minor modifications (Rothman...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2019
Entry Details
US Patent