BDBM28836 N-(4-fluoro-3-methylphenyl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine::triazolopyrimidine-based compound, DSM82

SMILES Cc1cc(Nc2ccc(F)c(C)c2)n2ncnc2n1

InChI Key InChIKey=XJVOUIFYVKYJOG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 28836   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Washington At Seattle

LigandPNGBDBM28836(N-(4-fluoro-3-methylphenyl)-5-methyl-[1,2,4]triazo...)
Affinity DataIC50: 4.60E+3nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei (strain Anka))
University of Washington At Seattle

LigandPNGBDBM28836(N-(4-fluoro-3-methylphenyl)-5-methyl-[1,2,4]triazo...)
Affinity DataIC50: 2.10E+4nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2009
Entry Details Article
PubMed