BDBM288400 US10087187, Compound 101

SMILES CCc1c(F)cccc1Cc1c(CNCCO)nc2c(N)cc(nn12)N1CCOCC1

InChI Key InChIKey=MIPLTGRLSDZLQU-UHFFFAOYSA-N

Data  5 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 288400   

LigandChemical structure of BindingDB Monomer ID 288400BDBM288400(US10087187, Compound 101)
Affinity DataKd:  6.20nMAssay Description:Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 288400BDBM288400(US10087187, Compound 101)
Affinity DataKd:  427nMAssay Description:Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 288400BDBM288400(US10087187, Compound 101)
Affinity DataKd:  724nMAssay Description:Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2019
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 288400BDBM288400(US10087187, Compound 101)
Affinity DataKd:  1.59E+3nMAssay Description:Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 288400BDBM288400(US10087187, Compound 101)
Affinity DataKd:  5.89E+3nMAssay Description:Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2019
Entry Details
US Patent