BDBM289115 N-(1H-benzo[d][1,2,3]triazol-6-yl)-6-hydroxy-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide::US10093658, Compound Formula (IIIa)

SMILES Oc1[nH]c(=O)[nH]c(=O)c1C(=O)Nc1ccc2n[nH]nc2c1

InChI Key InChIKey=GQERJQZROLADFV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 289115   

TargetSolute carrier family 22 member 12(Human)
Acquist

US Patent
LigandPNGBDBM289115(US10093658, Compound Formula (IIIa) | N-(1H-benzo[...)
Affinity DataIC50: 1.34E+3nMAssay Description:URAT1 (SLC22A12) activity was evaluated in a cellular uptake assay using a 96-well plate with stably transfected URAT-1/CHO cells. 3H-orotate was use...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM289115(US10093658, Compound Formula (IIIa) | N-(1H-benzo[...)
Affinity DataIC50: 8.93E+3nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
US Patent