BDBM289118 6-Hydroxy-4-oxo-N-(4-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)phenyl)-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide::US10093658, Compound Formula (Ig)

SMILES Oc1[nH]c(=S)[nH]c(=O)c1C(=O)Nc1ccc(cc1)-c1noc(=O)[nH]1

InChI Key InChIKey=XPCIURBMYXHSLB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 289118   

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM289118(US10093658, Compound Formula (Ig) | 6-Hydroxy-4-ox...)
Affinity DataIC50: 3.29E+3nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM289118(US10093658, Compound Formula (Ig) | 6-Hydroxy-4-ox...)
Affinity DataIC50: 8.01E+3nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Acquist

US Patent
LigandPNGBDBM289118(US10093658, Compound Formula (Ig) | 6-Hydroxy-4-ox...)
Affinity DataIC50: 1.50E+5nMAssay Description:URAT1 (SLC22A12) activity was evaluated in a cellular uptake assay using a 96-well plate with stably transfected URAT-1/CHO cells. 3H-orotate was use...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
US Patent