BDBM289119 6-hydroxy-2,4-dioxo-N-(4-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)phenyl)-1,2,3,4-tetrahydropyrimidine-5-carboxamide::US10093658, Compound Formula (If)

SMILES Oc1[nH]c(=O)[nH]c(=O)c1C(=O)Nc1ccc(cc1)-c1noc(=O)[nH]1

InChI Key InChIKey=OHLSWAFRGAWGMF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 289119   

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM289119(US10093658, Compound Formula (If) | 6-hydroxy-2,4-...)
Affinity DataIC50: 4.81E+3nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Acquist

US Patent
LigandPNGBDBM289119(US10093658, Compound Formula (If) | 6-hydroxy-2,4-...)
Affinity DataIC50: 7.60E+3nMAssay Description:URAT1 (SLC22A12) activity was evaluated in a cellular uptake assay using a 96-well plate with stably transfected URAT-1/CHO cells. 3H-orotate was use...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM289119(US10093658, Compound Formula (If) | 6-hydroxy-2,4-...)
Affinity DataIC50: 7.74E+3nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
US Patent