BDBM289213 US10093660, Example 2.36

SMILES Cc1cc(cc2ncnc(Nc3ccc(F)cc3O[C@H]3COC[C@@H]3O)c12)N=S1(=O)CCC1

InChI Key InChIKey=TZHJOOVYOQMSSP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 289213   

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Evotec Internatonal

US Patent
LigandPNGBDBM289213(US10093660, Example 2.36)
Affinity DataIC50: 3nMT: 2°CAssay Description:ASSAY SETUP: The inhibition of kinase activity of MNK2a was assessed using pre-activated GST-MNK2a. The white, 384-well OptiPlate F plates were purch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Evotec Internatonal

US Patent
LigandPNGBDBM289213(US10093660, Example 2.36)
Affinity DataIC50: 51nMAssay Description:MNK1 Data can be obtained from the MNK1 Z′-LYTE assay. The MNK1 Z′-LYTE screening protocol and assay conditions are also described on www...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
US Patent