BDBM290134 US9573958, Compound 32

SMILES CCOC(C)(C)C=C(C#N)C(=O)N1CCCC1Cn1c(NC(=O)c2ccc(Cl)cc2)nc2cc(CN[C@@H](C)C(C)(C)C)ccc12

InChI Key InChIKey=XEBOJRDCSPSTGD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 290134   

TargetTyrosine-protein kinase ITK/TSK(Human)
Principia Biopharma

US Patent
LigandPNGBDBM290134(US9573958, Compound 32)
Affinity DataIC50: 142nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent