BDBM292072 4-[5-(1-methyl-1H-indazol-5-yl)-2- {octahydro-1H-pyrrolo[3,4-c]pyridin-5-yl}- 1,3-thiazol-4-yl]benzonitrile::US10100046, Example 7::US9902719, Example 7

SMILES Cn1ncc2cc(ccc12)-c1sc(nc1-c1ccc(cc1)C#N)N1CCC2CNCC2C1

InChI Key InChIKey=DZUQALOGEVWHDI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 292072   

TargetLysine-specific histone demethylase 1A(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM292072(US10100046, Example 7 | 4-[5-(1-methyl-1H-indazol-...)
Affinity DataIC50: 100nMT: 2°CAssay Description:This assay determines the ability of a test compound to inhibit LSD1 demethylase activity. E. coli expressed full-length human LSD1 (Accession number...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2019
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM292072(US10100046, Example 7 | 4-[5-(1-methyl-1H-indazol-...)
Affinity DataIC50: 100nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent