BDBM292359 (S)-N-(2-((2,2-difluoroethyl)(ethyl)amino)propyl)-2-(5-(thiophen-2-yl)pyrazolo[1,5-a]pyrimidin-3-yl)isonicotinamide::US10100058, Example 15

SMILES CCN(CC(F)F)[C@@H](C)CNC(=O)c1ccnc(c1)-c1cnn2ccc(nc12)-c1cccs1

InChI Key InChIKey=FDTFKVHRCABZFD-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 292359   

LigandChemical structure of BindingDB Monomer ID 292359BDBM292359(US10100058, Example 15 | (S)-N-(2-((2,2-difluoroet...)
Affinity DataIC50: 8.34nMAssay Description:The biochemical activity of recombinant CaMKIIδ was measured by monitoring the phosphorylation of a target peptide using Homogenous Time Resolve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2019
Entry Details
US Patent