BDBM292707 N-((S)-2-(diethylamino)propyl)-2-(5-(5-fluorothiophen-2-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-6-((S)-2-(methylcarbamoyl)azetidin-1-yl)isonicotinamide::US10100058, Example 361

SMILES CCN(CC)[C@@H](C)CNC(=O)c1cc(nc(c1)-c1cnn2ccc(nc12)-c1ccc(F)s1)N1CC[C@H]1C(=O)NC

InChI Key InChIKey=XJGWFTPYUQAKSJ-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 292707   

LigandPNGBDBM292707(US10100058, Example 361 | N-((S)-2-(diethylamino)p...)
Affinity DataIC50: 0.150nMAssay Description:The biochemical activity of recombinant CaMKIIδ was measured by monitoring the phosphorylation of a target peptide using Homogenous Time Resolve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2019
Entry Details
US Patent

LigandPNGBDBM292707(US10100058, Example 361 | N-((S)-2-(diethylamino)p...)
Affinity DataEC50:  10nMAssay Description:CaMKII activity in neonatal rat ventricular myocytes (NRVM) was measured by monitoring the phosphorylation level of phospholamban using high-content ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2019
Entry Details
US Patent