BDBM292725 US10106501, Example B-2

SMILES CCOc1c(-c2ccc(Cl)cc2)c(=O)n(-c2ccc3nn(C)nc3c2)c2[nH]ncc12

InChI Key InChIKey=VRHYDLLTXRRGLH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 292725   

TargetS-adenosylmethionine synthase isoform type-2(Human)
Haihe Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 292725BDBM292725(US20260014125, Compound 127)
Affinity DataIC50: 12.4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2026
Entry Details US Patent