BDBM292851 US10106501, Example FV

SMILES C[C@@H](OCC12CCC(CC1)CO2)[C@H](NC(=O)[C@@H]5CN(c3cccc4nc(O)cnc34)CC57CN(C(=O)C6(C(F)(F)F)CC6)C7)C(=O)N9CCC(c8nccs8)CC9

InChI Key InChIKey=SIMRAMNMSOIQHQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 292851   

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Cedilla Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 292851BDBM292851(US20260014146, Compound I-45)
Affinity DataIC50: 1.00E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2026
Entry Details US Patent