BDBM292865 US10106501, Example GN

SMILES CC1(C)OC(=O)c2cc(Nc3nc(Nc4ccc5c(c4)CCNC5)ncc3Cl)ccc21

InChI Key InChIKey=DXHUJHAGTASXAO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 292865   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 292865BDBM292865(US20260015340, Compound 2)
Affinity DataIC50: 100nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2026
Entry Details US Patent

TargetMitogen-activated protein kinase kinase kinase 11 (MLK3)(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 292865BDBM292865(US20260015340, Compound 2)
Affinity DataIC50: 300nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2026
Entry Details US Patent