BDBM292866 US10106501, Example G1

SMILES CC1(C)OC(=O)c2ccc(Nc3ncc(Cl)c(Nc4ccc5c(c4)C(C)(C)OC5=O)n3)cc21

InChI Key InChIKey=FNNYJRBYDQFIFG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 292866   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 292866BDBM292866(US20260015340, Compound 3)
Affinity DataIC50: 750nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2026
Entry Details US Patent

TargetMitogen-activated protein kinase kinase kinase 11 (MLK3)(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 292866BDBM292866(US20260015340, Compound 3)
Affinity DataIC50: 1.00E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2026
Entry Details US Patent