BDBM29291 triazole, 3i

SMILES [O-][N+](=O)c1cnc(Sc2n[nH]c(=O)n2-c2ccc(OC(F)(F)F)cc2)s1

InChI Key InChIKey=GJKHPOFGVGSKEE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 29291   

TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM29291(triazole, 3i)
Affinity DataIC50: 130nMpH: 7.8 T: 2°CAssay Description:Compound was evaluated for its ability to disrupt the interaction of pepJIP1 with JNK1 by using DELFIA assay. DELFIA is a heterogeneous assay whereby...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM29291(triazole, 3i)
Affinity DataIC50: 2.00E+3nMAssay Description:Compound was evaluated for its ability to disrupt the interaction of pepJIP1 with JNK1 by using DELFIA assay. DELFIA is a heterogeneous assay whereby...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2009
Entry Details Article
PubMed