BDBM29298 triazole, 3p

SMILES [O-][N+](=O)c1cnc(Sc2n[nH]c(=O)n2-c2ccc(cc2)C(F)(F)F)s1

InChI Key InChIKey=QRIAVGWVUUQLHO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 29298   

TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM29298(triazole, 3p)
Affinity DataIC50: 75nMpH: 7.8 T: 2°CAssay Description:Compound was evaluated for its ability to disrupt the interaction of pepJIP1 with JNK1 by using DELFIA assay. DELFIA is a heterogeneous assay whereby...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM29298(triazole, 3p)
Affinity DataIC50: 3.00E+3nMAssay Description:Compound was evaluated for its ability to disrupt the interaction of pepJIP1 with JNK1 by using DELFIA assay. DELFIA is a heterogeneous assay whereby...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2009
Entry Details Article
PubMed