BDBM29317 2-amino-1,3,4-thiadiazole, 11

SMILES Nc1nnc(SCc2ccc(F)cc2)s1

InChI Key InChIKey=OPAKWVMMTCNRJQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 29317   

TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM29317(2-amino-1,3,4-thiadiazole, 11)
Affinity DataIC50: 1.00E+3nMAssay Description:Compound was evaluated for its ability to disrupt the interaction of pepJIP1 with JNK1 by using DELFIA assay. DELFIA is a heterogeneous assay whereby...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM29317(2-amino-1,3,4-thiadiazole, 11)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds were tested for their ability to inhibit JNK1 phosphorylation of ATF2 in the Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2009
Entry Details Article
PubMed