BDBM293815 3-({[(4R)-7-[(5-ethylpyridin-2-yl)(methyl)amino]-3,4-dihydro-2H-::US10106534, Example 157

SMILES CCc1ccc(nc1)N(C)c1ccc2[C@H](CNc3cnccc3C(O)=O)CCOc2c1

InChI Key InChIKey=IEMPFZUCIMFTHM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 293815   

TargetLysine-specific demethylase 4C(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM293815(3-({[(4R)-7-[(5-ethylpyridin-2-yl)(methyl)amino]-3...)
Affinity DataIC50: 550nMT: 2°CAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
US Patent

TargetLysine-specific demethylase 6B(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM293815(3-({[(4R)-7-[(5-ethylpyridin-2-yl)(methyl)amino]-3...)
Affinity DataIC50: 5.50E+3nMT: 2°CAssay Description:The enzymatic assay of JMJD3 activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
US Patent