BDBM293817 3-({[(1R)-6-[methyl(1-methyl-1H-pyrazol-4-yl)amino]-1,2,3,4-::US10106534, Example 159

SMILES CN(c1cnn(C)c1)c1ccc2[C@H](CNc3cnccc3C(O)=O)CCCc2c1

InChI Key InChIKey=NTDVVPRGWXWCET-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 293817   

TargetLysine-specific demethylase 4C(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM293817(3-({[(1R)-6-[methyl(1-methyl-1H-pyrazol-4-yl)amino...)
Affinity DataIC50: 550nMT: 2°CAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
US Patent

TargetLysine-specific demethylase 6B(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM293817(3-({[(1R)-6-[methyl(1-methyl-1H-pyrazol-4-yl)amino...)
Affinity DataIC50: 5.50E+3nMT: 2°CAssay Description:The enzymatic assay of JMJD3 activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
US Patent