BDBM29396 CHEMBL219406::tacrine-dihydropyridine hybrid (tacripyrine), 7
SMILES CCOC(=O)C1C(c2ccc(C)cc2)c2c(N)c3CCCCc3nc2N=C1C
InChI Key InChIKey=KSRAGVSAGPERSL-UHFFFAOYSA-N
Data 9 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 29396
Affinity DataIC50: 169nMpH: 7.2 T: 2°CAssay Description:The inhibitory activity of the compounds towards hAChE was determined following the method of Ellman using AChE from human serum and acetylthiocholin...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMpH: 7.2 T: 2°CAssay Description:The inhibitory activity of the compounds towards BuChE was determined following the method of Ellman using BuChE from human serum and butyrylthiochol...More data for this Ligand-Target Pair
Affinity DataIC50: 91nMAssay Description:The inhibitory activity of the compounds towards AChE was determined following the spectrophotometric method of Rappaport using purified AChE from Ee...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human serum BuChEMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human serum BuChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 91nMAssay Description:Inhibition of Electrophorus electricus AChEMore data for this Ligand-Target Pair
Affinity DataIC50: 91nMAssay Description:Inhibition of Electrophorus electricus AChE by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of human erythrocyte AChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 169nMAssay Description:Inhibition of human erythrocyte AChEMore data for this Ligand-Target Pair