BDBM294357 US9586950, 24::methyl 4-cyano-2-({(3R,6R)-1-[(2- fluoro-6-pyrimidin-2- ylphenyl)carbonyl]-6- methylpiperidin-3-yl}oxy)pyridine- 3-carboxylate
SMILES COC(=O)c1c(O[C@@H]2CC[C@@H](C)N(C2)C(=O)c2c(F)cccc2-c2ncccn2)nccc1C#N
InChI Key InChIKey=OHYMYLVQQRBIMN-NVXWUHKLSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 294357
Affinity DataKi: 0.420nMAssay Description:Described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-1430.More data for this Ligand-Target Pair
Affinity DataKi: 48nMAssay Description:Described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-1430.More data for this Ligand-Target Pair
Affinity DataIC50: 32.8nMAssay Description:. In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with ...More data for this Ligand-Target Pair
Affinity DataIC50: 380nMAssay Description:. In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with ...More data for this Ligand-Target Pair