BDBM29449 Pyrazolo[1,5-a]-1,3,5-triazine, 12-18

SMILES COc1cc(C)c(-c2c(C)nn3c(NC4CCC4)nc(C)nc23)c(OC)c1

InChI Key InChIKey=LMJYQQWNJXNUES-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 29449   

TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb

LigandPNGBDBM29449(Pyrazolo[1,5-a]-1,3,5-triazine, 12-18)
Affinity DataIC50: 17.4nMpH: 7.2 T: 2°CAssay Description:Naive rats were sacrificed by decapitation, and the brain and pituitary were collected. Slide-mounted brain sections were preincubated in an assay so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2009
Entry Details Article
PubMed