BDBM295194 US10112926, Example 78::trans-3-(6-Amino-5-(3-(2,2,2-trifluoroethyl)-1,2,4-oxadiazol-5-yl)pyridin-3-yl)-N-((1r,4r)-4-hydroxycyclohexyl)-4-methylbenzenesulfonamide

SMILES Cc1ccc(cc1-c1cnc(N)c(c1)-c1nc(CC(F)(F)F)no1)S(=O)(=O)N[C@H]1CC[C@H](O)CC1

InChI Key InChIKey=NSWURHBWYFQRSK-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 295194   

LigandPNGBDBM295194(trans-3-(6-Amino-5-(3-(2,2,2-trifluoroethyl)-1,2,4...)
Affinity DataIC50: 18nMpH: 7.5Assay Description:The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad, Calif., USA) (Cat. No. PV5099). The kit contains t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
US Patent

LigandPNGBDBM295194(trans-3-(6-Amino-5-(3-(2,2,2-trifluoroethyl)-1,2,4...)
Affinity DataIC50: 90nMpH: 7.5 T: 2°CAssay Description:The luminescence-based ATP detection reagent KinaseGlo was obtained from Promega, (Cat. No. V6714, Lot No. 236161) through Catalys, Wallisellen, Swit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
US Patent

LigandPNGBDBM295194(trans-3-(6-Amino-5-(3-(2,2,2-trifluoroethyl)-1,2,4...)
Affinity DataIC50: 100nMpH: 7.5Assay Description:The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad, Calif., USA) (Cat. No. PV5099). The kit contains t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
US Patent

TargetPhosphatidylinositol 4-kinase beta(Human)
Novartis

US Patent
LigandPNGBDBM295194(trans-3-(6-Amino-5-(3-(2,2,2-trifluoroethyl)-1,2,4...)
Affinity DataIC50: 490nMpH: 7.5 T: 2°CAssay Description:The luminescence-based ATP detection reagent KinaseGlo was obtained from Promega, (Cat. No. V6714, Lot No. 236161) through Catalys, Wallisellen, Swit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
US Patent

LigandPNGBDBM295194(trans-3-(6-Amino-5-(3-(2,2,2-trifluoroethyl)-1,2,4...)
Affinity DataIC50: 2.50E+3nMpH: 7.5 T: 2°CAssay Description:The luminescence-based ATP detection reagent KinaseGlo was obtained from Promega, (Cat. No. V6714, Lot No. 236161) through Catalys, Wallisellen, Swit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
US Patent

LigandPNGBDBM295194(trans-3-(6-Amino-5-(3-(2,2,2-trifluoroethyl)-1,2,4...)
Affinity DataIC50: 1.00E+4nMpH: 7.5 T: 2°CAssay Description:The luminescence-based ATP detection reagent KinaseGlo was obtained from Promega, (Cat. No. V6714, Lot No. 236161) through Catalys, Wallisellen, Swit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
US Patent