BDBM295261 6-(3-(2-aminopropan- 2-yl)phenoxy)-4-(6- methylpyridin-2- ylamino)pyridazine- 3-carboxamide::US10112928, Compound I-3

SMILES Cc1cccc(Nc2cc(Oc3cccc(c3)C(C)(C)N)nnc2C(N)=O)n1

InChI Key InChIKey=BDIDNIILKACPHV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 295261   

TargetTyrosine-protein kinase SYK [360-635](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM295261(US10112928, Compound I-3 | 6-(3-(2-aminopropan- 2-...)
Affinity DataIC50: 2.24E+3nMpH: 7.5Assay Description:SYK kinase assay is a standard kinase assay adapted to a 96 well plate format. This assay is performed in 96-well format for IC50 determination with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent