BDBM295271 6-chloro-4-(3,5- dimethylphenyl- amino)pyridazine-3- carboxamide::US10112928, Compound I-14

SMILES Cc1cc(C)cc(Nc2cc(Cl)nnc2C(N)=O)c1

InChI Key InChIKey=UKLHOTDGTGUKKX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 295271   

TargetTyrosine-protein kinase SYK [360-635](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM295271(US10112928, Compound I-14 | 6-chloro-4-(3,5- dimet...)
Affinity DataIC50: 124nMpH: 7.5Assay Description:SYK kinase assay is a standard kinase assay adapted to a 96 well plate format. This assay is performed in 96-well format for IC50 determination with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent