BDBM295278 2-(3-amino-propyl)-4- m-tolylamino- pyrimidine-5-carboxylic acid amide::US10112928, Compound I-22

SMILES Cc1cccc(Nc2nc(CCCN)ncc2C(N)=O)c1

InChI Key InChIKey=NRXXPOQMDMGPAR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 295278   

TargetTyrosine-protein kinase SYK [360-635](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM295278(US10112928, Compound I-22 | 2-(3-amino-propyl)-4- ...)
Affinity DataIC50: 2.54E+3nMpH: 7.5Assay Description:SYK kinase assay is a standard kinase assay adapted to a 96 well plate format. This assay is performed in 96-well format for IC50 determination with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent