BDBM295279 6-(2-aminoethylamino)- 4-(6-(2-hydroxypropan- 2-yl)pyridin-2- ylamino)pyridazine-3- carboxamide::US10112928, Compound I-23

SMILES CC(C)(O)c1cccc(Nc2cc(NCCN)nnc2C(N)=O)n1

InChI Key InChIKey=JHVZYRJWZZXANJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 295279   

TargetTyrosine-protein kinase SYK [360-635](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM295279(US10112928, Compound I-23 | 6-(2-aminoethylamino)-...)
Affinity DataIC50: 161nMpH: 7.5Assay Description:SYK kinase assay is a standard kinase assay adapted to a 96 well plate format. This assay is performed in 96-well format for IC50 determination with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent