BDBM295963 N-(2,3-dihydro- 1H-inden- 1-yl)-3- methoxy-4- (1H-pyrazol- 4-yl)benzamide::US10112939, Example 5

SMILES COc1cc(ccc1-c1cn[nH]c1)C(=O)NC1CCc2ccccc12

InChI Key InChIKey=GSVJTJKOPJWIKL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 295963   

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM295963(US10112939, Example 5 | N-(2,3-dihydro- 1H-inden- ...)
Affinity DataIC50: 32.2nMpH: 7.5Assay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent