BDBM295979 3-{1-[3-methoxy- 4-(1H-pyrazol- 4-yl)benzoyl] pyrrolidin-2- yl}phenol::US10112939, Example 21

SMILES COc1cc(ccc1-c1cn[nH]c1)C(=O)N1CCCC1c1cccc(O)c1

InChI Key InChIKey=FYKIIRCOAAERGQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 295979   

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM295979(US10112939, Example 21 | 3-{1-[3-methoxy- 4-(1H-py...)
Affinity DataIC50: 2.74nMpH: 7.5Assay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent