BDBM296010 3-[(2R)-4-hydroxy-1-[3- methoxy-4-(1H-pyrazol- 4-yl)benzoyl]pyrrolidin- 2-yl]-N-(2-methoxyethyl) benzamide::US10112939, Example 50

SMILES COCCNC(=O)c1cccc(c1)[C@H]1CC(O)CN1C(=O)c1ccc(-c2cn[nH]c2)c(OC)c1

InChI Key InChIKey=LKLDFFXOMCLDNI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 296010   

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM296010(US10112939, Example 50 | 3-[(2R)-4-hydroxy-1-[3- m...)
Affinity DataIC50: 5.10nMpH: 7.5Assay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent