BDBM296045 3-fluoro-4-{2- methoxy-4- [2-(3- methoxyphenyl) pyrrolidine-1- carbonyl] phenyl}pyridine::US10112939, Example 84

SMILES COc1cccc(c1)C1CCCN1C(=O)c1ccc(c(OC)c1)-c1ccncc1F

InChI Key InChIKey=ORZVPXAJJMRXLQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 296045   

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM296045(US10112939, Example 84 | 3-fluoro-4-{2- methoxy-4-...)
Affinity DataIC50: 24.1nMpH: 7.5Assay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent