BDBM296191 (3,3-dimethyl-2,3-dihydro-benzofuran-6- yl)-methyl-[4-(4-methyl-pyrido[3,4- d]pyrimidin-2-yloxy)-phenyl]-amine::US10112940, Example 116::US10202381, Example 116::US10208039, Example 116::US10611763, Example 116::US10815234, Example 116::US11535616, Example 116

SMILES CN(c1ccc(Oc2nc(O)c3ccncc3n2)cc1)c1ccc2c(OCC2(C)C)c1

InChI Key InChIKey=MOGTYGUBYMTHOM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 296191   

TargetLysine-specific demethylase 4C(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM296191(US10112940, Example 116 | (3,3-dimethyl-2,3-dihydr...)
Affinity DataIC50: 550nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate-format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetLysine-specific demethylase 4C(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM296191(US10112940, Example 116 | (3,3-dimethyl-2,3-dihydr...)
Affinity DataIC50: 550nMT: 2°CAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent