BDBM296828 1-(2-(Difluoromethoxy)phenyl)-8-(6-methoxypyridin-3-yl)-7-methyl-1,2,3,4-tetrahydroimidazo[1,2-a:5,4-b′]dipyridine::US10112944, Example 2

SMILES Cc1cc2nc3CCCN(c3n2cc1-c1ccc(CO)nc1)c1ccccc1OC(F)F

InChI Key InChIKey=SMFCQKJYSAWDPR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 296828   

TargetTumor necrosis factor(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM296828(1-(2-(Difluoromethoxy)phenyl)-8-(6-methoxypyridin-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Test compounds serially diluted in DMSO were plated in an assay plate (Labcyte, Cat. #LP-0200) at final concentrations ranging from 0.004 μM to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent