BDBM296834 1-(Isoquinolin-1-yl)-8-(6-methoxypyridin-3-yl)-1,2,3,4-tetrahydroimidazo [1,2-a:5,4-b′]dipyridine::US10112944, Example 8

SMILES COc1ccc(cn1)-c1ccc2nc3CCCN(c3n2c1)c1nccc2ccccc12

InChI Key InChIKey=YYNXSHZSOQSTRL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 296834   

TargetTumor necrosis factor(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM296834(1-(Isoquinolin-1-yl)-8-(6-methoxypyridin-3-yl)-1,2...)
Affinity DataIC50: 5.50E+3nMAssay Description:Test compounds serially diluted in DMSO were plated in an assay plate (Labcyte, Cat. #LP-0200) at final concentrations ranging from 0.004 μM to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent