BDBM296841 4-(5-(1-(2-(Difluoromethoxy)phenyl)-1,2,3,4-tetrahydroimidazo[1,2-a:5,4-b′]dipyridin-8-yl)pyrimidin-2-yl)morpholine::US10112944, Example 15

SMILES FC(F)Oc1ccccc1N1CCCc2nc3ccc(cn3c12)-c1cnc(nc1)N1CCOCC1

InChI Key InChIKey=VPZUJTMGMASNDY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 296841   

TargetTumor necrosis factor(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM296841(4-(5-(1-(2-(Difluoromethoxy)phenyl)-1,2,3,4-tetrah...)
Affinity DataIC50: 1.00E+3nMAssay Description:Test compounds serially diluted in DMSO were plated in an assay plate (Labcyte, Cat. #LP-0200) at final concentrations ranging from 0.004 μM to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent