BDBM296848 7-Chloro-1-(2-(difluoromethoxy)phenyl)-8-(6-methoxypyridin-3-yl)-1,2,3,4-tetrahydroimidazo[1,2-a:5,4-b′]dipyridine::US10112944, Example 22

SMILES COc1ccc(cn1)-c1cn2c3N(CCCc3nc2cc1Cl)c1ccccc1OC(F)F

InChI Key InChIKey=MDOOVNVPGLCIQS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 296848   

TargetTumor necrosis factor(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM296848(7-Chloro-1-(2-(difluoromethoxy)phenyl)-8-(6-methox...)
Affinity DataIC50: 5.50E+3nMAssay Description:Test compounds serially diluted in DMSO were plated in an assay plate (Labcyte, Cat. #LP-0200) at final concentrations ranging from 0.004 μM to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent