BDBM297337 5-((9H-purin-6-yl)amino)-2-methylisoindolin-1-one (Cpd. No. 2F)::US10112955, Example 2

SMILES CN1Cc2cc(Nc3ncnc4[nH]cnc34)ccc2C1=O

InChI Key InChIKey=CUXKGEHMNBXMDK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 297337   

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Effector Therapeutics

US Patent
LigandPNGBDBM297337(US10112955, Example 2 | 5-((9H-purin-6-yl)amino)-2...)
Affinity DataIC50: 550nMAssay Description:Compounds are screened for MNK inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent