BDBM29734 Pyridoimidazolone, 28c

SMILES Fc1cc(F)cc(CC(=O)Nc2ccc(Oc3ccnc4[nH]c(=O)[nH]c34)cc2)c1

InChI Key InChIKey=XNPMWPCNGMMORC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 29734   

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
The Institute of Cancer Research

LigandPNGBDBM29734(Pyridoimidazolone, 28c)
Affinity DataIC50: 1.00E+5nMAssay Description:The biological activities (IC50s) of the compounds were determined against the B-RAF (V600E) mutant enzyme in vitro. GST-MEK1, B-RAF (V600E), and inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed