BDBM297354 4-methyl-6-(pyrimidin-4-ylamino)-3,4-dihydroisoquinolin-1(2H)-one (Cpd. No. 22)::US10112955, Example 22

SMILES CC1CNC(=O)c2ccc(Nc3ccncn3)cc12

InChI Key InChIKey=WIPWOBQRZYJFLH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 297354   

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Effector Therapeutics

US Patent
LigandPNGBDBM297354(US10112955, Example 22 | 4-methyl-6-(pyrimidin-4-y...)
Affinity DataIC50: 550nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Effector Therapeutics

US Patent
LigandPNGBDBM297354(US10112955, Example 22 | 4-methyl-6-(pyrimidin-4-y...)
Affinity DataIC50: 5.05E+3nMAssay Description:Compounds are screened for MNK inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent