BDBM297401 3-Amino-6-(4-fluoro-phenyl)-5-trifluoromethyl-pyridine-2-carboxylic acid (2-hydroxy-2-methyl-propyl)-amide::US10117858, Example 11::US20240058315, Example 11

SMILES CC(C)(O)CNC(=O)c1nc(-c2ccc(F)cc2)c(cc1N)C(F)(F)F

InChI Key InChIKey=GJQPKGWZJDQMIQ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 297401   

LigandPNGBDBM297401(US10117858, Example 11 | 3-Amino-6-(4-fluoro-pheny...)
Affinity DataEC50:  37nMAssay Description:Fischer Rat Thyroid (FRT) epithelial cells, stably expressing human ΔF508-CFTR were used as monolayer cultures on permeable supports. Cl− ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

LigandPNGBDBM297401(US10117858, Example 11 | 3-Amino-6-(4-fluoro-pheny...)
Affinity DataEC50:  37nMAssay Description:Fischer Rat Thyroid (FRT) epithelial cells, stably expressing human ΔF508-CFTR were used as monolayer cultures on permeable supports. Cl− ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
US Patent