BDBM297555 2-{[4-[4-(2-dimethylamino- phenyl)-piperidin-1-yl]-2-(1- trifluoromethyl-cyclopentyl)- quinazolin-6-yl]-methyl-amino}- ethanol::US10118902, Example 57::US10584103, Example 57

SMILES CN(C)c1ccccc1C1CCN(CC1)c1nc(nc2ccc(cc12)N(C)CCO)C1(CCCC1)C(F)(F)F

InChI Key InChIKey=XHWPDJBOSAONHF-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 297555   

TargetNeurotensin receptor type 1(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM297555(US10118902, Example 57 | 2-{[4-[4-(2-dimethylamino...)
Affinity DataEC50:  1.25E+3nMAssay Description:NTSR1 (NTR1) CHO cells are plated in 20 uL of assay media containing Ham's F12 supplemented with 10% fetal bovine serum and 0.4 mg/mL G418 at a c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetNeurotensin receptor type 1(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM297555(US10118902, Example 57 | 2-{[4-[4-(2-dimethylamino...)
Affinity DataEC50:  1.25E+3nMAssay Description:NTSR1 (NTR1) CHO cells are plated in 20 μL of assay media containing Ham's F12 supplemented with 10% fetal bovine serum and 0.4 mg/mL G418 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2020
Entry Details
US Patent