BDBM297721 2-[(2-(1-Fluoro-cyclopropyl)-4- {4-[2-(2-fluoro-ethoxy)-phenyl]- piperidin-1-yl}-quinazolin-6-yl)- methyl-amino]-ethanol::US10118902, Example 225::US10584103, Example 225

SMILES CN(CCO)c1ccc2nc(nc(N3CCC(CC3)c3ccccc3OCCF)c2c1)C1(F)CC1

InChI Key InChIKey=MEHIBYHOXJIZGX-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 297721   

TargetNeurotensin receptor type 1(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM297721(US10118902, Example 225 | 2-[(2-(1-Fluoro-cyclopro...)
Affinity DataEC50:  1.25E+3nMAssay Description:NTSR1 (NTR1) CHO cells are plated in 20 μL of assay media containing Ham's F12 supplemented with 10% fetal bovine serum and 0.4 mg/mL G418 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2020
Entry Details
US Patent

TargetNeurotensin receptor type 1(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM297721(US10118902, Example 225 | 2-[(2-(1-Fluoro-cyclopro...)
Affinity DataEC50:  1.25E+3nMAssay Description:NTSR1 (NTR1) CHO cells are plated in 20 uL of assay media containing Ham's F12 supplemented with 10% fetal bovine serum and 0.4 mg/mL G418 at a c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent