BDBM298471 US10125101, Example 21

SMILES Cc1cnc(nc1)-c1cc(C)c(c(C)c1)-c1ccc(F)c2[C@@H](CCc12)Nc1ccc(nc1)[C@H]1C[C@@H]1C(O)=O

InChI Key InChIKey=NIWIPOJZYSARNQ-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 298471   

TargetFree fatty acid receptor 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM298471(US10125101, Example 21)
Affinity DataEC50:  2nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetCytochrome P450 2C8(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM298471(US10125101, Example 21)
Affinity DataIC50: 1.50E+4nMAssay Description:The inhibition of cytochrome P450 2C8-isoenzyme catalyzed deethylation of amodiaquine by the test compound is assayed at 37° C. with human liver micr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetCytochrome P450 2C9(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM298471(US10125101, Example 21)
Affinity DataIC50: 3.60E+4nMAssay Description:The inhibition of cytochrome P450 2C9-isoenzyme catalyzed hydroxylation of diclofenac by the test compound is assayed at 37° C. with human liver micr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent