BDBM299047 US10125118, Example 453::US10947215, Example 453

SMILES Cn1cc(cn1)-c1cnc(N)c(c1)C(=O)N[C@H]1COC[C@@H]1OCc1ccc(cc1)-c1ccc(cc1)C(C)(C)N1CCN(CCO)CC1

InChI Key InChIKey=OHEDTEGRXGHQDP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 299047   

TargetTyrosine-protein kinase Mer(Human)
Dong-A Socio Holdings

US Patent
LigandPNGBDBM299047(US10125118, Example 453 | US10947215, Example 453)
Affinity DataIC50: 10nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetTyrosine-protein kinase Mer/receptor UFO(Human)
Dong-A Socio Holdings

US Patent
LigandPNGBDBM299047(US10125118, Example 453 | US10947215, Example 453)
Affinity DataIC50: 10nMAssay Description:For the SAR (structure-activity relationship) and compound screening, LanthaScreen TR-FRET (Time-Resolved fluorescence energy transfer) assay was emp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent