BDBM299207 (1R,5S,7S)-3-oxa-9-azabicyclo [3.3.1]nonan-7-yl 1-(pyridin-3- yl)-1H-indole-3-carboxylate::US10125145, Cpd. No. 5

SMILES CN1C2COCC1CC(C2)OC(=O)c1cn(-c2cccnc2)c2ccccc12

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 299207   

Target5-hydroxytryptamine receptor 3A(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM299207(US10125145, Cpd. No. 5 | (1R,5S,7S)-3-oxa-9-azabic...)
Affinity DataIC50: 0.620nMAssay Description:The 5-HT3 antagonist activity of the compounds of the invention was determined by measuring the ability of the compounds to inhibit the calcium flux ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2019
Entry Details
US Patent