BDBM299365 6-(3-chloro-5- fluoro-phenyl) quinazolin-4- amine::US9592235, Example 171::US9855269, Compound 15

SMILES Nc1ncnc2ccc(cc12)-c1cc(F)cc(Cl)c1

InChI Key InChIKey=QWGJBVJDHIRFFJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 299365   

LigandPNGBDBM299365(US9592235, Example 171 | 6-(3-chloro-5- fluoro-phe...)
Affinity DataIC50: 226nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
US Patent

LigandPNGBDBM299365(US9592235, Example 171 | 6-(3-chloro-5- fluoro-phe...)
Affinity DataIC50: 226nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent