BDBM299404 N-[3-(4-amino- quinazolin-6- yl)-5-fluoro- phenyl]- 4-methyl- morpholine-2- carboxamide::US9592235, Example 197::US9855269, Compound 44

SMILES CN1CCOC(C1)C(=O)Nc1cc(F)cc(c1)-c1ccc2ncnc(N)c2c1

InChI Key InChIKey=LEOHPTOLHHNLPQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 299404   

LigandPNGBDBM299404(US9592235, Example 197 | N-[3-(4-amino- quinazolin...)
Affinity DataIC50: 264nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

LigandPNGBDBM299404(US9592235, Example 197 | N-[3-(4-amino- quinazolin...)
Affinity DataIC50: 264nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
US Patent