BDBM299435 N-[3-(4-amino- quinazolin-6-yl) phenyl]-2- (dimethylamino) acetamide::US9592235, Example 224::US9855269, Compound 71

SMILES CN(C)CC(=O)Nc1cccc(c1)-c1ccc2ncnc(N)c2c1

InChI Key InChIKey=TXHGOKBFQKJFFM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 299435   

LigandPNGBDBM299435(US9592235, Example 224 | N-[3-(4-amino- quinazolin...)
Affinity DataIC50: 263nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
US Patent

LigandPNGBDBM299435(US9592235, Example 224 | N-[3-(4-amino- quinazolin...)
Affinity DataIC50: 263nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent