BDBM299504 6-[3-[6-(dimethyl- amino)-2-pyridyl]- 1-piperidyl] pyrido[3,2-d] pyrimidin- 4-amine::US9592235, Example 277::US9855269, Compound 124

SMILES CN(C)c1cccc(n1)C1CCCN(C1)c1ccc2ncnc(N)c2n1

InChI Key InChIKey=SQZDWLWLHXRZJE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 299504   

LigandPNGBDBM299504(US9592235, Example 277 | 6-[3-[6-(dimethyl- amino)...)
Affinity DataIC50: 290nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

LigandPNGBDBM299504(US9592235, Example 277 | 6-[3-[6-(dimethyl- amino)...)
Affinity DataIC50: 290nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
US Patent